Sertraline Side-effects: And Everything Else

Sertraline aka Zoloft is a type of antidepressant. It is not known exactly how the drug works. But it is thought to affect chemicals in the brain that control mood and emotion. However, it is important to consider sertraline side effects before you start taking this drug. This blog post will discuss what sertraline does, who should take it, how to take it, possible side effects, and more!

What Is Sertraline?

sertraline formula


Sertraline is a prescription medication that belongs to the class of drugs called selective serotonin reuptake inhibitors (SSRIs). It is used to treat depression, obsessive-compulsive disorder (OCD), panic disorder, posttraumatic stress disorder (PTSD), and social anxiety disorder.

What Does Sertraline Treat?

Sertraline is used to treat several mental health conditions. It is most commonly prescribed for depression, but can also be effective in treating OCD, panic disorder, PTSD, and social anxiety disorder.

How Should I Take Sertraline?

sertraline dosage

  • Sertraline should be taken orally, with or without food.
  • It is usually prescribed in doses of 25 mg to 200 mg per day, depending on your individual needs.

What Happens If I Miss A Dose Of Sertraline?

If you forget to take a dose of sertraline, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular schedule.

NOTE: Do not take two doses of this medication at the same time.

What Happens If I Overdose With Sertraline?

If you overdose on sertraline, seek emergency medical help immediately. The symptoms of an overdose may include nausea, vomiting, drowsiness, or loss of consciousness.

Important Information To Know About Sertraline

sertraline management

There are some important things you should know about sertraline before taking it.

Interact With Other Drugs

This drug can interact with other medications or supplements you are currently taking. It is important to make sure your doctor and pharmacist know any drugs or supplements you take regularly so they can avoid harmful interactions between them.

Sertraline Side effects

side effects sertraline

Second, there may be side effects associated with the use of this medication. Some people experience mild side effects such as nausea, diarrhea, or headache.

However, some more serious side effects can occur, including suicidal thoughts and serotonin syndrome.

If you experience any of these more serious side effects, it is important to stop taking the medication and seek medical help immediately.

Finally, sertraline should not be taken during pregnancy unless it is prescribed by a doctor.

Specific Concerns About Sertraline And Pregnancy

Yes, there are specific concerns about sertraline and pregnancy.

First, pregnant women should not take this medication without the guidance of their healthcare provider because some studies have shown that taking SSRIs during pregnancy can increase the risk of birth defects.

Second, there are some concerns about the use of sertraline during breastfeeding because SSRIs can pass through breast milk to a nursing baby. However, more research is needed to determine if this medication affects breastfed babies or not.

NOTE: If you are thinking about breastfeeding while taking this drug, talk with your healthcare provider about the potential risks and benefits.

What Should I Avoid While Taking Sertraline?

There are several things you should avoid while taking sertraline.

  • First, be careful when drinking alcohol while taking this medication. Combining sertraline with alcohol can increase the risk of serious side effects.
  • Second, do not take this drug with other SSRIs or MAO inhibitors because it can cause serious interactions.
  • Finally, be careful when driving or operating heavy machinery while taking this medication because it can cause drowsiness and dizziness.

What Are The Possible Side Effects Of Sertraline?

There are several possible side effects associated with the use of sertraline. Some people experience mild side effects such as nausea or headache, while others may experience more severe reactions like anxiety and agitation.

Common Sertraline Side effects


  • Nausea
  • Dry Mouth
  • Headache
  • Fatigue
  • Insomnia
  • Diarrhea or Constipation

Severe Sertraline Side effects

  • Suicidal thoughts
  • Serotonin syndrome

What Is Sertraline Syndrome?

Serotonin syndrome is a rare but potentially life-threatening condition that can occur when taking certain medications, including sertraline. This condition occurs when there is too much serotonin in the body.

Symptoms can include fever, racing heartbeat, changes in blood pressure, excessive sweating, and agitation. If you experience any of these symptoms while taking this drug, seek medical help immediately.

NOTE: It is important to discuss all other prescription and non-prescription medications you are taking with your healthcare provider before starting sertraline. Some medications can increase the risk of serotonin syndrome or other serious side effects when taken together with this drug.

Risks For Taking Sertraline For Long Periods Of Time

Yes, some risks come with taking sertraline for a long period.

  • First, you should not stop this medication suddenly because doing so could cause withdrawal symptoms. Instead, talk to your healthcare provider about how to taper off the medication slowly and safely.
  • Second, there is some concern that taking SSRIs for a long period may increase the risk of suicidal thoughts or behaviors. However, more research will determine if this is true.

Medications That May Worsen Sertraline Side-effects

Several medications may interact with sertraline or worsen sertraline side effects.

  • First, be sure to tell your healthcare provider about all the medications you are taking, including prescription and over-the-counter drugs, vitamins, and supplements.
  • Second, some medications may increase the risk of serious side effects if taken together with sertraline. These include other antidepressants, antipsychotics, and seizure medications.
  • Finally, be careful when taking St. John’s wort while on sertraline because it can decrease the effectiveness of this medication.

How Long Does It Take To Work?

sertraline side effects

It usually takes several weeks for sertraline to start working properly. If you do not feel any better after taking this medication for several weeks, talk to your healthcare provider or pharmacist.

Sertraline comes in tablet form and is usually taken once daily with food. The recommended starting dose of sertraline is 50 mg per day, although doses up to 200 mg per day may be prescribed by your doctor based on your individual needs.


Sertraline is a medication that is used to treat depression, anxiety, and other conditions. It usually takes several weeks for sertraline to start working properly. Some people experience mild side effects such as nausea or headache. While others may experience more severe reactions like anxiety and agitation. Some risks may come with taking sertraline for a long period. So be sure to talk to your healthcare provider before starting this medication.

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